Having poor quality eggs or semen may result in infertility among couples. Registered in the UK, Clinic Center offers infertility treatments such as embryo, egg and sperm donation in Turkey. To get further information on egg, sperm and embryo donation cost, you can simply contact us online.
We offer our patients an affordable high-quality treatment standards in our facilities in Istanbul. In our centre, all medical departments work in close cooperation to deliver the best treatment options for our patients. If you like to be more informed about bone transplantation process, you can send us your medical documents and our patient representatives in Clinic Center will deliver more information as soon as possible.
What is Bone Marrow Transplant?
Bone marrow is the soft, sponge like tissues inside your bones which creates cells that produce blood cells. A bone marrow transplant is the replacement of the stem cells which are damaged or destroyed by disease, infection, or chemotherapy. Clinic Center, registered in the UK, offers all-inclusive cancer treatment packages abroad to achieve a healthy body. Cooperating with the best doctors in Turkey, Clinic Center provides international patients with best price Bone Marrow Transplant results.
Types of Bone Marrow Transplant in Turkey
Autologous bone marrow transplant: This is also called an AUTO transplant. Autologous stem cells are collected from your own body
Allogeneic bone marrow transplant: This is also called an ALLO transplant. Allogenic stem cells are collected from another person, called a donor. The chances of a brother or sister being a suitable match are approximately 1 in 4 and for more distant relatives it is less likely. Most times, the donor’s genes must at least partly match your genes. Special tests are done to see if a donor is a good match for you. Usually, the cells collected through an ALLO transplant are not frozen.
Haploidentical (Half-Matched) bone marrow transplant: Sometimes it is not possible to find a close match. Then, a haploidentical transplant may be an option. This is a type of allogeneic transplant when the donor partially matches with the patient, half of his HLA level to be exact.
How is a Bone Marrow Transplant Done?
There are two ways of collecting stem cells:
Bone Marrow Harvest: In this method, transplant cells are taken from the patient’s hip bone with a needle and syringe. The procedure is performed under general anesthesia.
Peripheral Blood Stem Cell Collection: In this method, stem cells are collected from the blood. This technique does not require surgery. However, prior to the collection, the donor is given a medication to increase the growth rate and initiate separation of stem cells from the bone into the blood for collection.
After bone marrow collection, there are two possible routes to be followed;
Ablative ALLO transplant: uses high-dose chemotherapy
Reduced intensity ALLO transplant: Smaller doses of chemotherapy
Finally, your transplant cells will be put into your bloodstream through the catheter.
Who is a Candidate for Bone Marrow Transplant?
Bone marrow transplants are performed when a person’s marrow isn’t healthy enough to function properly. This may occur due to several reason like aplastic anemia, which is a disorder in which the marrow stops making new blood cells; cancers like leukemia, lymphoma, and multiple myeloma; bone marrow damaged with chemotherapy, congenital neutropenia, sickle cell anemia and thalassemia.
What are the Risks of Bone Marrow Transplant?
The likelihood of developing a complication depends on various factors such as age, overall health, type of the procedure and the disease of the patient. If you are receiving a transplant through stem cells collected from a donor, there is always a risk of developing graft-versus-host disease (GVHD). This condition can be simply described as the attacking of the donor stem cells to your own body’s tissues and organs, newly transplanted cells are there to make up your new immune system and as they may perceive your tissues as something foreign and dangerous, they attack your own body organisms. Your body may develop GVHD during the first few months after your transplant (Acute GVHD) or over a longer period of time.
Other complications are:
Stem Cell Failure
How Long Does It Take to Recover from a Bone Marrow Transplant?
It mostly depends on the type of the transplant you had, for autologous transplant patients, it may take 2-3 months and for allogeneic bone marrow transplant it may take up to 6 months to be able to fully return to the normal daily life activities.
Bone Marrow Transplant Cost in Turkey
Healthcare costs in some parts of the world are excessively soaring, patients may have to pay extreme prices for their treatment in their own country and some may not even be able to afford the care they need. Turkey presents an alternative solution for this problem by being more affordable in many regards compared to the other countries. You can have your treatment by our accomplished highly experienced doctors in our well-equipped hospitals for much reasonable prices.
Bone Marrow Transplant Recovery and Aftercare
Usually people stay in the hospital for two to three weeks after the procedure. During the recovery, you receive antibiotics and other medications. This also includes medications to prevent graft-versus-host disease. You may also get blood transfusions through your catheter if needed.
Fast Facts About Bone Marrow Transplant
|Procedure:||Transplantation of stem cells through a large vein in the chest after pre-transplant treatments of chemotherapy and also radiotherapy for some cases.|
|Stay:||4 weeks of hospitalization|
|Anesthesia:||General Anesthesia for Bone Harvesting,|
|Recovery:||Physically 2-3 months, it may take up to one year to return normal life|
|Pain:||Depending on the procedure specifics and the patient, from moderate to severe pain|
|Side Effects:||Nausea and vomiting, Diarrhea, Hair loss, Mouth sores or ulcers, Infection, Bleeding, Infertility or sterility, Anemia, Fatigue, Cataracts, Organ complications|
|Duration:||Pre-Transplant treatment 5 to 7 days, Transplant 1 hour|
|Complications:||Severe and continuous bleeding, Infection, Liver problems, Skin rash, Diarrhea, Infertility or sterility, Cataracts, Muscle spasms, Leg cramps, Numbness in extremities, Secondary cancers, Death|
Bone Marrow Transplant FAQ
How long does Bone Marrow Transplant take?
Bone Morrow Transplant takes about 1 hour.
Will I feel any pain?
Depending on the age group and the pain tolerance of the patient, bone marrow treatment can be said to be moderately and severely painful.
How to Prepare for a Bone Marrow Transplant?
As a first step, before your transplant, you’ll undergo several tests to examine what type of bone marrow cells you need. After that You may need to have radiation or chemotherapy treatment in order to destroy the cancerous cells.
Bone marrow transplant treatments last for a week. You may need to make some arrangements for your comfort before you are admitted to hospital.
How is Bone marrow transplant is performed?
Bone marrow transfusion is very similar to blood transfusion. If you are receiving cells from a donor, they are collected one or two days before the procedure. But if it is your own cells that are being used, then they will be brought from the stem cell bank. A needle called a central venous catheter, or a port will be inserted on the right side of your upper chest for transfusion. The catheter will stay there for a couple of days, because bone marrow transfusion is done over several sessions.
How long does it take to recover from bone marrow transplant?
It changes from person to person, but most people are expected to stay in the hospital for at least 30 days. After your discharge, it may take several more months (or even years) for your immune to fully recover. Your situation will be constantly monitored during the recovery process.
Is smoking risky for stem cell transplant patients?
It is more likely for smokers to experience transplant complications or more experience complications more severely. Smokers are highly advised to stop smoking.
Is it safe to get pregnant during blood and marrow transplant treatment?
The medications used during your treatment can be harmful to an unborn child. You should not become pregnant or father a child during your treatment.
When can I return work after bone marrow transplant?
After an autologous transplant, it takes about two to three months to recover physically, yet it can take up to a year to completely return your normal life. It is most commonly takes one to two months to be able to return work.
After an allogeneic stem cell, the recovery period is longer and potential for side effects is greater. Patients are expected to stay in the hospital for about four to six weeks. For allogeneic stem cell transplant patient; recovery period may go up to six months.
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. All content, including text, graphics, images, and information, contained on or available through this web site is for general information purposes only. It is not advice on your specific needs and circumstances. It does not replace the need for you to have a thorough consultation, so you should get advice from a suitably qualified doctor or surgeon. Please bear in mind that as with all operations, there are risks involved in having cancer treatment surgery.